Publications 1990-1999
Project |
Publication Information (Click the authors' names to retrieve the abstract) |
Flow cytometry |
Dynamics of glucose uptake by single Escherichia coli cells. |
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Abu-Absi,N.R. & Srienc,F. (1999) Cell cycle events and cell cycle dependent processes in eukaryotic cells. Encyclopedia of Cell Technology (ed. by S.W.D.Flickinger and), John Whiley. |
Polyhydroxyalkanoate production |
Jackson,J.K. & Srienc,F. (1999) Effects of recombinant modulation of the phbCAB operon copy number on PHB synthesis rates in Ralstonia eutropha. J.Biotechnol. 68, 49-60. |
Population modeling |
Mantzaris,N.V.,Daoutidis,P., Srienc,F., & Fredrickson,A.G. (1999) Growth processes in a cascade of bioreactors: Mathematical models. AIChE J. 45, 164-176. |
Population modeling |
Mantzaris,N.V., Daoutidis,P., Srienc,F., & Fredrickson,A.G. (1999) Growth processes in a cascade of bioreactors: Comparison of modeling approaches. AIChE J. 45, 177-189 |
Population modeling |
Mantzaris,N.V., Liou,J.J., Daoutidis,P., & Srienc,F. (1999) Numerical solution of a mass structured cell population balance model in an environment of changing substrate concentration. J.Biotechnol. 71, 157-174. |
Flow cytometry |
Natarajan,A., Dunny,G., & Srienc,F. (1999) Flow cytometric analysis of growth of two Streptococcus gordonii derivatives. J.Microbiol.Meth. 34, 223-233. |
Flow cytometry |
Natarajan,A. & Srienc,F.(1999) Dynamics of glucose uptake by single Escherichia coli cells. Metabol.Eng. 1, 320- 333. |
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Ramkrishna,D. & Srienc,F. (1999) In honor of Arnold G. Fredrickson. J.Biotechnol. 71 , 3-5. |
Modeling |
Ramkrishna,D. & Srienc,F. (1999) Special Issue - Modelling in biochemical engineering. J.Biotechnol. 71, 1-1. |
Population modeling, Flow cytometry |
Srienc,F. (1999) Cytometric data as the basis for rigorous models of cell population dynamics. J.Biotechnol. 71, 233-238. |
Polyhydroxyalkanoate production |
Production of two phase polyhydroxyalkanoic acid granules in Ralstonia eutropha. |
Flow cytometry |
Zhao R, Natarajan A, Srienc F. A flow injection flow cytometry system for on-line monitoring of bioreactors. |
Polyhydroxyalkanoate production |
Kelley,A.S., Jackson,D.E., Macosko,C., & Srienc,F. (1998) Engineering the composition of co-polyesters synthesized by Alcaligenes eutrophus. Polym.Degrad.Stab. 59, 187-190. |
Flow cytometry |
Quantitating secretion rates of individual cells: design of secretion assays. |
Polyhydroxyalkanoate production, Metabolic modeling |
Metabolic modeling of polyhydroxybutyrate biosynthesis. |
Flow cytometry |
Natarajan A, Subramanian S, Srienc F. Comparison of mutant forms of the green fluorescent protein as expression markers in Chinese hamster ovary (CHO) and Saccharomyces cerevisiae cells. |
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Liou JJ, Fredrickson AG, Srienc F. Selective synchronization of Tetrahymena pyriformis cell populations and cell growth kinetics during the cell cycle. |
Polyhydroxyalkanoate production |
Hahn JJ, Eschenlauer AC, Narrol MH, Somers DA, Srienc F. Growth kinetics, nutrient uptake, and expression of the Alcaligenes eutrophus poly(beta-hydroxybutyrate) synthesis pathway in transgenic maize cell suspension cultures. |
Flow cytometry |
Hatzis,C., Fredrickson,A.G., & Srienc,F. (1997) Cell-cycle analysis in phagotrophic microorganisms from flow cytometric histograms. J.Theor.Biol. 186, 131-144. |
Population modeling |
Liou,J.J., Srienc,F., & Fredrickson,A.G. (1997) Solutions of population balance models based on a successive generations approach. Chem.Eng.Sci. 52, 1529-1540. |
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Scheper,T., Freitag,R., & Srienc,F. (1997) On-line and off-line process analysis. Mammalian Cell Biotechnology in Protein Production (ed. by H.Hauser and R.Wagner), pp. 373-410. Walter de Gruyter, Berlin, New York. |
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Subramanian,S. & Srienc,F. (1997) The green fluorescent protein (Gfp) as a tool for the analysis of gene expression in mammalian cells. Cell & Tissue Culture: Laboratory Procedures (ed. by A.Doyle and J.B.Griffiths), pp. 1-14. |
Flow cytometry |
Quantitative analysis of transient gene expression in mammalian cells using the green fluorescent protein. |
Polyhydroxyalkanoate production |
Eschenlauer AC, Stoup SK, Srienc F, Somers DA. Production of heteropolymeric polyhydroxyalkanoate in Escherichia coli from a single carbon source. |
Polyhydroxyalkanoate production |
Leaf TA, Peterson MS, Stoup SK, Somers D, Srienc F. Saccharomyces cerevisiae expressing bacterial polyhydroxybutyrate synthase produces poly-3-hydroxybutyrate. |
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Schweizer L, Yerk-Davis GL, Phillips RL, Srienc F, Jones RJ. Dynamics of maize endosperm development and DNA endoreduplication. |
Flow cytometry |
Tracking of individual cell cohorts in asynchronous Saccharomyces cerevisiae populations. |
Population modeling |
Hatzis C, Srienc F, Fredrickson AG. Multistaged corpuscular models of microbial growth: Monte Carlo simulations. |
Flow cytometry |
Cherlet,M., Kromenaker,S.J., & Srienc,F. (1995) Surface IgG content of murine hybridomas: direct evidence for variation of antibody secretion rates during the cell cycle. Biotechnol.Bioeng. 47, 535-540. |
Polyhydroxyalkanoate production |
Novel methods to synthesize polyhydroxyalkanoates. |
Flow cytometry |
Stability of producer hybridoma cell lines after cell sorting: a case study. |
Flow cytometry |
Effect of lactic acid on the kinetics of growth and antibody production in a murine hybridoma: secretion patterns during the cell cycle. |
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Sun L, Jacobson BA, Dien BS, Srienc F, Fuchs JA. Cell cycle regulation of the Escherichia coli nrd operon: requirement for a cis-acting upstream AT-rich sequence. |
Flow cytometry |
Cell cycle kinetics of the accumulation of heavy and light chain immunoglobulin proteins in a mouse hybridoma cell line. |
Flow cytometry |
Dien BS, Peterson MS, Srienc F. Cell-cycle analysis of Saccharomyces cerevisiae. |
Population modeling |
Hatzis,C., Srienc,F., & Fredrickson,A.G. (1994) Feeding heterogeneity in ciliate populations: effects of culture age and nutritional state. Biotechnol.Bioeng. 43, 371-380. |
Flow cytometry |
Sweeney,P.J., Srienc,F., & Fredrickson,A.G. (1994) Measurement of unequal DNA partitioning in Tetrahymena pyriformis using slit-scanning flow cytometry. Biotechnol.Progr. 10, 19-25. |
Population modeling |
Hatzis,C., Sweeney,P.J., Srienc,F., & Fredrickson,A.G. (1993) Determination of cellular rate distributions in microbial cell populations: feeding rates of ciliated protozoa. Biotechnol.Bioeng. 42, 284-294. |
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Kromenaker,S.J. & Srienc,F. (1993) Cell-Cycle Dynamics of Antibody Formation in Hybridomas. Animal Cell Technology: Basic & Applied Aspects (ed. by S.Kaminogawa, A.Ametani, and S.Hachimura), pp. 535-541. Kluwer Acad., Dordrecht. |
Flow cytometry |
Kinetics of the cell cycle of Saccharomyces cerevisiae. |
Flow cytometry |
Fredrickson AG, Hatzis C, Srienc F. A statistical analysis of flow cytometric determinations of phagocytosis rates. |
Flow cytometry |
Jones,R.J., Srienc,F., & Roessler,J.R. (1992) Flow cytometric determination of light scattering and absorbance properties of starch granules. Starch/ Starke 44, 243-247. |
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Kowles,R.V., McMullen,M.D., Yerk,G.L., Phillips,R.L., Kraemer,S., & Srienc,F. (1992) Endosperm mitotic activity and endoreduplication in maize affected by defective kernel mutations. Genome 35, 68-77. |
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Kowles,R.V., Yerk,G.L., Srienc,F., & Phillips,R.L. (1992) Maize endosperm tissue as an endoreduplication system. Genetic engineering: principles and methods (ed. by J.K.Setlow), pp. 65-88. |
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Srienc,F. (1992) Bookreview: Bioreactor Design Fundamentals by N.G. McDuffie. AIChE J. |
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Dynamics of activation of a galactose-inducible promoter in Saccharomyces cerevisiae. |
Flow cytometry |
Bromodeoxyuridine labeling and flow cytometric identification of replicating Saccharomyces cerevisiae cells: lengths of cell cycle phases and population variability at specific cell cycle positions. |
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Block,D. & Srienc,F. (1991) Rapid identification and isolation of zygotes and the kinetics of mating in Saccharomyces cerevisiae. Biotechnol.Tech. 5, 95-100. |
Flow cytometry |
Kromenaker,S.J. & Srienc,F. (1991) Cell-cycle dependent protein accumulation by producer and non- producer murine hybridoma cell lines: a population analysis. Biotechnol.Bioeng. 38, 665-677. |
Population modeling |
Eitzman,P.D. & Srienc,F. (1990) Simulation of size distributions in growing yeast populations. UMSI.Res.Rep.Series. 90, 78-78. |
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Kowles,R.V., Srienc,F., & Phillips,R.L. (1990) Endoreduplication of nuclear DNA in the developing maize endosperm. Dev.Genet. 11, 125-132. |
Population modeling |
Hatzis C, Sweeney PJ, Srienc F, Fredrickson AG. A discrete, stochastic model for microbial filter feeding: a model for feeding of ciliated protists on spatially uniform, nondepletable suspensions. |
Flow cytometry |
Block DE, Eitzman PD, Wangensteen JD, Srienc F. Slit scanning of Saccharomyces cerevisiae cells: quantification of asymmetric cell division and cell cycle progression in asynchronous culture. |
Flow cytometry |
Flow cytometric study of hybridoma cell culture: correlation between cell surface fluorescence and IgG production rate. |
Flow cytometry |
Lavin DP, Fredrickson AG, Srienc F. Flow cytometric measurement of rates of particle uptake from dilute suspensions by a ciliated protozoan. |
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Lavin,D.P., Hatzis,C., Srienc,F., & Fredrickson,A.G. (1990) Size limitations on the uptake of particles by populations of Tetrahymena cells. J.Protozool. 37, 157-163. |
Flow cytometry |
Lavin,D.P., Fredrickson,A.G., Srienc,F., Sweeney,P.J., & Hatzis,C. (1990) Measurements of distributions of cellular process rates in growing microbial populations. Proc.Asia-Pacif.Biochem.Eng.Conf.Seoul.,Korea. 288-290. |