Publications 1990-1999

Project

Publication Information (Click the authors' names to retrieve the abstract)

Flow cytometry

Natarajan A, Srienc F.

Dynamics of glucose uptake by single Escherichia coli cells.
Metab Eng. 1999 Oct;1(4):320-33.

 

Abu-Absi,N.R. & Srienc,F. (1999)

Cell cycle events and cell cycle dependent processes in eukaryotic cells. Encyclopedia of Cell Technology (ed. by S.W.D.Flickinger and), John Whiley.

Polyhydroxyalkanoate production

Jackson,J.K. & Srienc,F. (1999)

Effects of recombinant modulation of the phbCAB operon copy number on PHB synthesis rates in Ralstonia eutropha. J.Biotechnol. 68, 49-60.

Population modeling

Mantzaris,N.V.,Daoutidis,P., Srienc,F., & Fredrickson,A.G. (1999)

Growth processes in a cascade of bioreactors: Mathematical models. AIChE J. 45, 164-176.

Population modeling

Mantzaris,N.V., Daoutidis,P., Srienc,F., & Fredrickson,A.G. (1999)

Growth processes in a cascade of bioreactors: Comparison of modeling approaches. AIChE J. 45, 177-189

Population modeling

Mantzaris,N.V., Liou,J.J., Daoutidis,P., & Srienc,F. (1999)

Numerical solution of a mass structured cell population balance model in an environment of changing substrate concentration. J.Biotechnol. 71, 157-174.

Flow cytometry

Natarajan,A., Dunny,G., & Srienc,F. (1999)

Flow cytometric analysis of growth of two Streptococcus gordonii derivatives. J.Microbiol.Meth. 34, 223-233.

Flow cytometry

Natarajan,A. & Srienc,F.(1999)  Dynamics of glucose uptake by single Escherichia coli cells. Metabol.Eng. 1, 320- 333.

 

Ramkrishna,D. & Srienc,F. (1999)

In honor of Arnold G. Fredrickson. J.Biotechnol. 71 , 3-5.

Modeling

Ramkrishna,D. & Srienc,F. (1999)

Special Issue - Modelling in biochemical engineering. J.Biotechnol. 71, 1-1.

Population modeling, Flow cytometry

Srienc,F. (1999)

Cytometric data as the basis for rigorous models of cell population dynamics. J.Biotechnol. 71, 233-238.

Polyhydroxyalkanoate production

Kelley AS, Srienc F.

Production of two phase polyhydroxyalkanoic acid granules in Ralstonia eutropha.
Int J Biol Macromol. 1999 Jun-Jul;25(1-3):61-7.

Flow cytometry

Zhao R, Natarajan A, Srienc F.

A flow injection flow cytometry system for on-line monitoring of bioreactors.
Biotechnol Bioeng. 1999 Mar 5;62(5):609-17.

Polyhydroxyalkanoate production

Kelley,A.S., Jackson,D.E., Macosko,C., & Srienc,F. (1998)

Engineering the composition of co-polyesters synthesized by Alcaligenes eutrophus. Polym.Degrad.Stab. 59, 187-190.

Flow cytometry

Frykman S, Srienc F.

Quantitating secretion rates of individual cells: design of secretion assays.
Biotechnol Bioeng. 1998 Jul 20;59(2):214-26.

Polyhydroxyalkanoate production, Metabolic modeling

Leaf TA, Srienc F.

Metabolic modeling of polyhydroxybutyrate biosynthesis.
Biotechnol Bioeng. 1998 Mar 5;57(5):557-70.

Flow cytometry

Natarajan A, Subramanian S, Srienc F.

Comparison of mutant forms of the green fluorescent protein as expression markers in Chinese hamster ovary (CHO) and Saccharomyces cerevisiae cells.
J Biotechnol. 1998 Jun 11;62(1):29-45.

 

Liou JJ, Fredrickson AG, Srienc F.

Selective synchronization of Tetrahymena pyriformis cell populations and cell growth kinetics during the cell cycle.
Biotechnol Prog. 1998 May-Jun;14(3):450-6.

Polyhydroxyalkanoate production

Hahn JJ, Eschenlauer AC, Narrol MH, Somers DA, Srienc F.

Growth kinetics, nutrient uptake, and expression of the Alcaligenes eutrophus poly(beta-hydroxybutyrate) synthesis pathway in transgenic maize cell suspension cultures.
Biotechnol Prog. 1997 Jul-Aug;13(4):347-54.

Flow cytometry

Hatzis,C., Fredrickson,A.G., & Srienc,F. (1997)

Cell-cycle analysis in phagotrophic microorganisms from flow cytometric histograms. J.Theor.Biol. 186, 131-144.

Population modeling

Liou,J.J., Srienc,F., & Fredrickson,A.G. (1997)

Solutions of population balance models based on a successive generations approach. Chem.Eng.Sci. 52, 1529-1540.

 

Scheper,T., Freitag,R., & Srienc,F. (1997)

On-line and off-line process analysis. Mammalian Cell Biotechnology in Protein Production (ed. by H.Hauser and R.Wagner), pp. 373-410. Walter de Gruyter, Berlin, New York.

 

Subramanian,S. & Srienc,F. (1997)

The green fluorescent protein (Gfp) as a tool for the analysis of gene expression in mammalian cells. Cell & Tissue Culture: Laboratory Procedures (ed. by A.Doyle and J.B.Griffiths), pp. 1-14.

Flow cytometry

Subramanian S, Srienc F.

Quantitative analysis of transient gene expression in mammalian cells using the green fluorescent protein.
J Biotechnol. 1996 Aug 20;49(1-3):137-51.

Polyhydroxyalkanoate production

Eschenlauer AC, Stoup SK, Srienc F, Somers DA.

Production of heteropolymeric polyhydroxyalkanoate in Escherichia coli from a single carbon source.
Int J Biol Macromol. 1996 Aug;19(2):121-30.

Polyhydroxyalkanoate production

Leaf TA, Peterson MS, Stoup SK, Somers D, Srienc F.

Saccharomyces cerevisiae expressing bacterial polyhydroxybutyrate synthase produces poly-3-hydroxybutyrate.
Microbiology. 1996 May;142 ( Pt 5):1169-80.

 

Schweizer L, Yerk-Davis GL, Phillips RL, Srienc F, Jones RJ.

Dynamics of maize endosperm development and DNA endoreduplication.
Proc Natl Acad Sci U S A. 1995 Jul 18;92(15):7070-4.

Flow cytometry

Porro D, Srienc F.

Tracking of individual cell cohorts in asynchronous Saccharomyces cerevisiae populations.
Biotechnol Prog. 1995 May-Jun;11(3):342-7.

Population modeling

Hatzis C, Srienc F, Fredrickson AG.

Multistaged corpuscular models of microbial growth: Monte Carlo simulations.
Biosystems. 1995;36(1):19-35.

Flow cytometry

Cherlet,M., Kromenaker,S.J., & Srienc,F. (1995)

Surface IgG content of murine hybridomas: direct evidence for variation of antibody secretion rates during the cell cycle. Biotechnol.Bioeng. 47, 535-540.

Polyhydroxyalkanoate production

Jackson DE, Srienc F.

Novel methods to synthesize polyhydroxyalkanoates.
Ann N Y Acad Sci. 1994 Nov 30;745:134-48.

Flow cytometry

Kromenaker SJ, Srienc F.

Stability of producer hybridoma cell lines after cell sorting: a case study.
Biotechnol Prog. 1994 May-Jun;10(3):299-307.

Flow cytometry

Kromenaker SJ, Srienc F.

Effect of lactic acid on the kinetics of growth and antibody production in a murine hybridoma: secretion patterns during the cell cycle.
J Biotechnol. 1994 Apr 30;34(1):13-34.

 

Sun L, Jacobson BA, Dien BS, Srienc F, Fuchs JA.

Cell cycle regulation of the Escherichia coli nrd operon: requirement for a cis-acting upstream AT-rich sequence.
J Bacteriol. 1994 Apr;176(8):2415-26.

Flow cytometry

Kromenaker SJ, Srienc F.

Cell cycle kinetics of the accumulation of heavy and light chain immunoglobulin proteins in a mouse hybridoma cell line.
Cytotechnology. 1994;14(3):205-18.

Flow cytometry

Dien BS, Peterson MS, Srienc F.

Cell-cycle analysis of Saccharomyces cerevisiae.
Methods Cell Biol. 1994;42 Pt B:457-75.

Population modeling

Hatzis,C., Srienc,F., & Fredrickson,A.G. (1994)

Feeding heterogeneity in ciliate populations: effects of culture age and nutritional state. Biotechnol.Bioeng. 43, 371-380.

Flow cytometry

Sweeney,P.J., Srienc,F., & Fredrickson,A.G. (1994)

Measurement of unequal DNA partitioning in Tetrahymena pyriformis using slit-scanning flow cytometry. Biotechnol.Progr. 10, 19-25.

Population modeling

Hatzis,C., Sweeney,P.J., Srienc,F., & Fredrickson,A.G. (1993)

Determination of cellular rate distributions in microbial cell populations: feeding rates of ciliated protozoa. Biotechnol.Bioeng. 42, 284-294.

 

Kromenaker,S.J. & Srienc,F. (1993)

Cell-Cycle Dynamics of Antibody Formation in Hybridomas. Animal Cell Technology: Basic & Applied Aspects (ed. by S.Kaminogawa, A.Ametani, and S.Hachimura), pp. 535-541. Kluwer Acad., Dordrecht.

Flow cytometry

Srienc F, Dien BS.

Kinetics of the cell cycle of Saccharomyces cerevisiae.
Ann N Y Acad Sci. 1992 Oct 13;665:59-71.

Flow cytometry

Fredrickson AG, Hatzis C, Srienc F.

A statistical analysis of flow cytometric determinations of phagocytosis rates.
Cytometry. 1992;13(4):423-31.

Flow cytometry

Jones,R.J., Srienc,F., & Roessler,J.R. (1992)

Flow cytometric determination of light scattering and absorbance properties of starch granules. Starch/ Starke 44, 243-247.

 

Kowles,R.V., McMullen,M.D., Yerk,G.L., Phillips,R.L., Kraemer,S., & Srienc,F. (1992)

Endosperm mitotic activity and endoreduplication in maize affected by defective kernel mutations. Genome 35, 68-77.

 

Kowles,R.V., Yerk,G.L., Srienc,F., & Phillips,R.L. (1992)

Maize endosperm tissue as an endoreduplication system. Genetic engineering: principles and methods (ed. by J.K.Setlow), pp. 65-88.

 

Srienc,F. (1992)

Bookreview: Bioreactor Design Fundamentals by N.G. McDuffie. AIChE J.

 

Eitzman PD, Srienc F.

Dynamics of activation of a galactose-inducible promoter in Saccharomyces cerevisiae.
J Biotechnol. 1991 Nov;21(1-2):63-81.

Flow cytometry

Dien BS, Srienc F.

Bromodeoxyuridine labeling and flow cytometric identification of replicating Saccharomyces cerevisiae cells: lengths of cell cycle phases and population variability at specific cell cycle positions.
Biotechnol Prog. 1991 Jul-Aug;7(4):291-8.

 

Block,D. & Srienc,F. (1991)

Rapid identification and isolation of zygotes and the kinetics of mating in Saccharomyces cerevisiae. Biotechnol.Tech. 5, 95-100.

Flow cytometry

Kromenaker,S.J. & Srienc,F. (1991)

Cell-cycle dependent protein accumulation by producer and non- producer murine hybridoma cell lines: a population analysis. Biotechnol.Bioeng. 38, 665-677.

Population modeling

Eitzman,P.D. & Srienc,F. (1990)

Simulation of size distributions in growing yeast populations. UMSI.Res.Rep.Series. 90, 78-78.

 

Kowles,R.V., Srienc,F., & Phillips,R.L. (1990)

Endoreduplication of nuclear DNA in the developing maize endosperm. Dev.Genet. 11, 125-132.

Population modeling

Hatzis C, Sweeney PJ, Srienc F, Fredrickson AG.

A discrete, stochastic model for microbial filter feeding: a model for feeding of ciliated protists on spatially uniform, nondepletable suspensions.
Math Biosci. 1990 Dec;102(2):127-81.

Flow cytometry

Block DE, Eitzman PD, Wangensteen JD, Srienc F.

Slit scanning of Saccharomyces cerevisiae cells: quantification of asymmetric cell division and cell cycle progression in asynchronous culture.
Biotechnol Prog. 1990 Nov-Dec;6(6):504-12.

Flow cytometry

Sen S, Hu WS, Srienc F.

Flow cytometric study of hybridoma cell culture: correlation between cell surface fluorescence and IgG production rate.
Enzyme Microb Technol. 1990 Aug;12(8):571-6.

Flow cytometry

Lavin DP, Fredrickson AG, Srienc F.

Flow cytometric measurement of rates of particle uptake from dilute suspensions by a ciliated protozoan.
Cytometry. 1990;11(8):875-82.

 

Lavin,D.P., Hatzis,C., Srienc,F., & Fredrickson,A.G. (1990)

Size limitations on the uptake of particles by populations of Tetrahymena cells. J.Protozool. 37, 157-163.

Flow cytometry

Lavin,D.P., Fredrickson,A.G., Srienc,F., Sweeney,P.J., & Hatzis,C. (1990)

Measurements of distributions of cellular process rates in growing microbial populations. Proc.Asia-Pacif.Biochem.Eng.Conf.Seoul.,Korea. 288-290.