Hackel Peptide
Hackel Lab


We are currently seeking multiple postdoctoral scholars.

Please e-mail hackel@umn.edu with CV and letter.

Our research program, in the Department of Chemical Engineering and Materials Science at the University of Minnesota, applies protein engineering technologies to develop physiological molecular targeting agents for molecular diagnostics and targeted therapy, with a focus on oncology and infectious disease. We balance (1) fundamental study of molecular evolution and protein biophysics, which empowers our protein engineering efforts; and (2) application of these advances to develop non-invasive diagnostics and therapeutics for clinical challenges in oncology and infectious disease. Our research is highly interdisciplinary including scientists, engineers, and collaborators across the Chemical Engineering and Materials Science, Biomedical Engineering, Pharmacology, Chemistry, Oncology, Physiology, Medicinal Chemistry, Radiology, and more. We appreciate the support of the National Institutes of Health, the American Cancer Society, the University of Minnesota, and biotechnology partners.


Congratulations to Adelyn Crabtree for defending her thesis.

Congratulations to Dan Tresnak for defending his thesis.

Congratulations Joe Hassler for presenting "Grafted Polymer Architecture as a Tool to Inform Mechanisms of Polymer-Cell Membrane Interactions" at APS Meeting 2021.

Matt, Seth, Katherine, Dan, and Alex's paper was published in ACS Synthetic Biology.

Andrew, Abby, and Sadie's paper was published in Cell Chemical Biology.

Alex, Katherine, and Siddharth's paper was published in PNAS.