Hackel Peptide
Hackel Lab


We are currently seeking multiple postdoctoral scholars.

Please e-mail hackel@umn.edu with CV and letter.

Our research program, in the Department of Chemical Engineering and Materials Science at the University of Minnesota, applies protein engineering technologies to develop physiological molecular targeting agents for molecular diagnostics and targeted therapy, with a focus on oncology and infectious disease. We balance (1) fundamental study of molecular evolution and protein biophysics, which empowers our protein engineering efforts; and (2) application of these advances to develop non-invasive diagnostics and therapeutics for clinical challenges in oncology and infectious disease. Our research is highly interdisciplinary including scientists, engineers, and collaborators across the Chemical Engineering and Materials Science, Biomedical Engineering, Pharmacology, Chemistry, Oncology, Physiology, Medicinal Chemistry, Radiology, and more. We appreciate the support of the National Institutes of Health, the American Cancer Society, the University of Minnesota, and biotechnology partners.


Seth's paper was published in Applied and Experimental Microbiology.

Alex, Patrick, and Katelynn's paper was published in ACS Combinatorial Science.

Larry, Patrick, and Alexandra's paper (in collaboration with the Willmann lab at Stanford) was published in ACS Combinatorial Science.

Justin's paper was published in Bioinformatics.

Welcome Adam, Joe, and Paul, the newest graduate students in the Hackel lab.

Hackel group, in collaboration with the Sachs Lab in Biomedical Engineering, awarded NIH R21 grant to study TNF receptor antagonists and activity-based ligand engineering.

Sadie successfully defends her doctoral thesis. Congratulations!

Pin-Kuang successfully defends his doctoral thesis. Congratulations!